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$30.00

A New Convenient Way to Enjoy Akuamma!

  • 30 Capsules Per Bottle
  • 600mg Per Capsule
  • 100% Vegan, Gluten Free, Non GMO Capsules
  • No Fillers, 100% Pure Akuamma

Pain Relief, Stimulation, Energy and Mood Enhancement

Buy with confidence, all of our products are tested and trusted for purity and potency. Break Free Herbs is owned and operated in the USA. Fast shipping.

*This package is sold as a research product without directions or claims. Keep out of reach of children and pets.

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Description

Akuamma – Picralima Capsules, Convenient & Effective.

Too busy to be measuring out your Akuamma all the time? Looking to take your Akuamma on the go? Introducing Akuamma Capsules, a great new way to enjoy the benefits of this wonderful seed. Each bottle contains 30 capsules and each capsule has 600mg (A little more than 1/2 Gram) of finely ground Akuamma powder. Try Akuamma Capsules from Break Free Herbs today!

Akuamma

A Popular Pain Relief Alternative.

  • Pain Relief
  • Stimulation
  • Mood Enhancement

Our Akuamma is a perfect fine grind suitable for many purposes. We test all of our products for impurities and potency and take pride in the fact that all of our items are of the highest quality. We do not stock mediocre or untested products.

Akuammine is the most abundant active alkaloid found in the seeds from the tree Picralima nitida, commonly known as Akuamma. 

The seeds from this tree are utilized in every day medicine all over West Africa, most commonly in Ghana, the Ivory Coast & Nigeria.  The seeds are made in to a fine powder and taken orally.

Akuamma is used as a painkiller and for its antipyretic, anti-diabetic and anti-inflammatory effects.

A more advanced Ghanaian hospital began producing 250mg capsules of powdered Akuamma, and distributed them all over the country where they became greatly accepted as a safe and effective pain relief product. This then led scientists to try and dig deeper in to the active alkaloids of this wonderful plant.

The alkaloids

Below are the main alkaloids in the Akuamma seeds. The Akuammine portion act similarly to opioids. The strongest activity comes from delta and particularly kappa receptors. 

  • Akuammidine – is the primary alkaloid within the seeds, making up 0.56% of the powder.  It is structurally similar to both yohimbine and mitragynine [similar to Kratom].  This alkaloid showed a preference for opioid binding sites with Ki values of 0.6, 2.4 and 8.6 micro M at mu-, delta- and kappa-opioid binding sites, respectively.  This makes it a kappa agonist with a bit of delta and even less mu activity.  Akuammidine has hypotensive, skeletal muscle relaxant and local analgesic activities. Its local analgesic activity is about 3 times as potent as codeine. 
  • Akuammine – akuammine also showed high affinity for mu-opioid binding sites (Ki 0.5 microM) but was an antagonist at mu-opioid receptors with a pK(B) of 5.7 against the selective mu-opioid receptor agonist enkephalin (DAMGO).   Its other properties, however, suggest it has agonistic properties at other opioid sites.  Akuammine has strong sympathomimetic and local analgesic activities.

*This product is not intended for internal use. It is offered for research, reference standard, or as an incense product for external use only.

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